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AUR2CDS0FT · 27.09, Auriense 2–0 CD San JoseHOR1GUI0FT · 27.09, Hortaleza 1–0 GüímarSAN1PRA5FT · 27.09, San Rafael 1–5 PratTAL1ALC2FT · 27.09, Talayuela 1–2 AlcazarMAR1TAV1FT · 27.09, Maracena 1–1 TavernesBAZ1ATL2FT · 03.10, Baztán 1–2 Atletico CalatayudCEU1LEB2FT · 03.10, Ceuta 6 de Junio 1–2 LebrijanaTED2ANA5FT · 03.10, Tedeón 2–5 AnaitasunaNOJ1RIB1FT · 04.10, Noja 1–1 Ribadesella CFCDS1AUR0FT · 04.10, CD San Jose 1–0 AurienseALC1TAL0FT · 04.10, Alcazar 1–0 TalayuelaATL0PIN3FT · 04.10, Atlético Melilla 0–3 PinatarTAV0MAR0Pens · 04.10, Tavernes 0–0 Maracena (4–2)GUI3HOR3AET · 11.10, Güímar 3–3 HortalezaPRA5SAN0FT · 11.10, Prat 5–0 San RafaelCUA–GIR–27.10 17:30, Cuarte ––– GironaCAL–EUR–27.10 18:00, Calamocha ––– Europa FcPIN–ELC–27.10 18:00, Pinatar ––– ElcheSES–ESP–27.10 18:00, Sestao River ––– EspanyolCAS–ALM–27.10 18:45, Castellonense ––– AlmeriaATL–MIR–27.10 19:00, Atlético Tordesillas ––– MirandesCIU–RAY–27.10 19:00, Ciudad de Lucena ––– Rayo MajadahondaGIM–CUL–27.10 19:00, Gimnástica Segoviana ––– Cultural LeonesaLLA–PON–27.10 19:00, Llanera ––– PonferradinaRSD–PAL–27.10 19:00, RSD Alcalá ––– Las PalmasDON–EXT–27.10 19:30, Don Benito ––– Extremadura 1924MAN–SAN–27.10 19:30, Manresa ––– Sant AndreuALC–MAL–27.10 20:00, Alcazar ––– MalagaARO–PON–27.10 20:00, Arosa ––– PontevedraATL–COR–27.10 20:00, Atlético Paso ––– Cordoba
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Real Betis vs Sevilla - Copa del Rey, Round of 16 (Sun, 16 January 2022)

Copa del Rey Round of 16
Full time
Real Betis Sevilla
2 1
Estadio Benito Villamarín, Sevilla